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  1. The m6A hypermethylation-induced PIR overexpression regulates …

    Jul 28, 2025 · Here, we identified Pirin (PIR) as a key oncogenic factor in UM through comprehensive multi-omics analyses, revealing that PIR is significantly upregulated and …

  2. Role and mechanism of piR-0228 targeting RIPK1 to

    Jul 18, 2025 · In addition, we identified and confirmed that RIPK1 is a downstream target of piR-0228 and is negatively regulated by it through the integration of bioinformatics analysis. …

  3. Glacial geomorphosites in the Greater Himalayan and Pir Panjal …

    Oct 1, 2025 · This study investigates the glacial geomorphosites of the Greater Himalayan Range and Pir Panjal Range in the Kashmir Valley, highlighting their poten…

  4. piR-hsa-35410 promotes triple-negative breast cancer progression …

    In summary, our study revealed that piR-35410 promotes the malignant progression of TNBC by regulating PFKL-mediated glycolysis. These findings provide valuable insights into the role of …

  5. CD40 induces PIR-A+ macrophages to promote chronic allograft …

    Mar 26, 2025 · Results CD40 and PIR-A were highly expressed and colocalized in macrophage-infiltrating allograft in the mouse model. CD40-CD40L blockade inhibited PIR-A expression …

  6. piR-hsa-35410 promotes triple-negative breast cancer progression …

    This study identified piR-hsa-35410 (hereafter piR-35410) with aberrant expression and aimed to further elucidate its biological functions and mechanisms in TNBC. In TNBC, the elevated …

  7. The piR-31115-PIWIL4 complex promotes the migration of the …

    Mar 20, 2025 · In vitro cell experiments disclosed that piR-31115 promotes the migration of MDA-MB-231 cells through PIWIL4. Co-IP suggested that piR-31115 facilitates the binding of …

  8. Self-supporting flexible electrode-integrated microfluidic ECL …

    The integration of electrochemiluminescence (ECL) sensor into microfluidic chip can greatly improve the convenience and reliability in bioanalysis, en…

  9. Novel occupancy detection method based on convolutional neural …

    Oct 1, 2024 · To improve the occupancy detection accuracy, this study proposes an innovative occupant number detection approach involving a temporal sequential analysis of occupancy …

  10. The piR-31115-PIWIL4 complex promotes the migration of the …

    Mar 20, 2025 · Pir-31115 enhances the interaction of piwil4 with hsp90aa1. (a) the ion flow map of all the signals collected by mass spectrometry analyses of the piwil4 complex …