Interstate 81 northbound is shut down from mile marker 291 to 296 in Shenandoah County due to a tractor-trailer crash.

An early morning truck crash on the southern leg of southbound I-81 in Maryland has spilled hazardous paint. One lane ...

An early morning truck crash on the southern leg of southbound I-81 in Maryland has spilled hazardous paint and closed ...

The ensuing response, including crash and environmental cleanup, as well as other crashes along I-81 contributed to the lengthy interstate closure, Maryland State Highway Administration spokesperson ...

Virginia State Police are investigating a crash on Interstate 81 involving a tractor-trailer carrying cattle. The crash ...

Delays are increasing following a crash on Interstate 81 in Cumberland County. Video above: Headlines from WGAL News 8 Today.

A crash on Interstate 81 North in Sullivan County has backed up traffic for miles, according to the Tennessee Department of ...

The Pennsylvania Department of Transportation (PennDOT) is advising drivers of an upcoming lane restriction in Lackawanna ...

“Saturday Night Live” on Sept. 28 featured Maya Rudolph reprising her role as Vice President Kamala Harris, and saw Dana ...

Update around 11 p.m. Thursday: Southbound Interstate 81 was fully reopened in the Williamsport area as of about 10:30 p.m. Thursday, according to Maryland State Police. The southbound lanes had ...

A stretch of Interstate 81 in Lebanon County shut down after a vehicle towing a camper overturned, according to PennDOT.