An LC×LC–HRMS method was developed for the characterization of phenolic compounds in cannabis, with flavoalkaloids identified for the first time.

A closing session on Day 1 of HPLC on Monday, June 15, 2025, ended with a topic that is on everyone’s lips in separation science: oligonucleotide analysis. The session was chaired by two luminaries in ...

Shimadzu Scientific Instruments introduces the Nexera-e Comprehensive Two-Dimensional Liquid Chromatograph (2D-LC), which offers a powerful separation method for the most complex sample matrices. The ...

Compared with the conventional liquid chromatography/mass spectrometry metabolomics, our multidimensional chromatography approach performed better in discriminating multiple ginseng varieties. This ...

Combining these methods in two-dimensional liquid chromatography (2D-LC) helps understand the interrelationship between molar mass distribution and chemical composition distribution, providing a ...

(2021) Development of Immunoprecipitation—Two-Dimensional Liquid Chromatography—Mass Spectrometry Methodology as Biomarker Read-Out to Quantify Phosphorylated Tau in Cerebrospinal Fluid from Alzheimer ...

1. Introduction. The versatility of two-dimensional liquid chromatography (2D-LC) is widely acknowledged, despite usually being used to only analyze complex mixtures with a large number of peaks. 1, 2 ...