MRI scans of self-described extroverts revealed a significantly larger medial orbitofrontal cortex, the area just above and behind the eye socket. This area is involved with keeping track of ...

Flipping the switch on fewer than 500 neurons dramatically reduces the alcohol consumption of mice. This novel finding could ...

The model also assumes that the orbitofrontal cortex and the medial prefrontal cortex use different internal models of reward timing, with the latter being more sensitive to variations in timing ...

Importantly, the model assumed that stimulation of the orbital frontal cortex and the medial prefrontal cortex separately increased the initial reward probability from 75% to 94% only in that ...

More information: Wenhui Zong et al, Hippocampal output suppresses orbitofrontal cortex schema cell formation, Nature Neuroscience (2025). DOI: 10.1038/s41593-025-01928-z.

Recent research has suggested that the orbitofrontal cortex is a critical node in determining the economic values of offers presented to a decision-maker. Using an economic decision-making task ...

Electrically stimulating the lateral orbitofrontal cortex, a brain area behind the eyes, improves the moods of people with depression, according to a study published yesterday (November 29) in Current ...

A new study linked chronic pain to activity in the orbitofrontal cortex, an area involved in emotion regulation, self-evaluation and decision making. By Priyanka Runwal Researchers have for the ...

Orbitofrontal cortex modulates auditory cortical sensitivity and sound perception in Mongolian gerbils. Curr Biol. 2024. doi: 10.1016/j.cub.2024.06.036. This article has been republished from the ...