Pass rates on the Legal Practice Course (LPC) have tumbled to just 42%, as the old route to qualification continues its slow wind-down and more students head down the Solicitors Qualifying Examination ...

Liz Simmons is an education staff writer at Forbes Advisor. She has written about higher education and career development for various online publications since 2016. She earned a master’s degree in ...

Thoreau wrote: “All change is a miracle to contemplate, but it is a miracle which is taking place every instant.” Right now, you may be struggling with interpersonal conflict, insomnia, low ...

Objectives: In this work we aimed to document the role of Lp-PLA2 in calcific aortic valve disease (CAVD). Background: CAVD is a chronic disorder, which is characterized by pathological mineralization ...

The steroid hormone progesterone (P4) regulates multiple aspects of reproductive and metabolic physiology. Classical P4 signaling operates through nuclear receptors that regulate transcription. In ...

A study in Acta Pharmaceutica Sinica B discusses the identification of a natural PLA2 inhibitor from the marine fungus Aspergillus sp. c1 for MAFLD treatment that suppressed lipotoxicity by inhibiting ...

ABSTRACT: Chagas disease (CD) affects 21 countries in the Americas and is caused by the parasite Trypanosoma cruzi. A key molecule involved in CD is lysophosphatidylcholine (LPC), which has been ...

ABSTRACT: Chagas disease (CD) affects 21 countries in the Americas and is caused by the parasite Trypanosoma cruzi. A key molecule involved in CD is lysophosphatidylcholine (LPC), which has been ...

The nomination of novel Lp-PLA2 inhibitor DPT0415 for the treatment of DR & DME. DPT0415 is a highly potent, selective and safe Lp-PLA2 inhibitor with sufficient target engagement at a dose of 0.3 mpk ...

Beijing DP Technology Co. Ltd. has nominated DPT-0415, a novel small molecule targeting lipoprotein‐associated phospholipase A2 (Lp-PLA2), as a preclinical candidate for the treatment of diabetic ...