The field of cancer treatment saw a variety of advancements in 2025, from new dedicated centers to approved treatments to ...

Ethan was diagnosed with diffuse midline glioma (DMG), a cancer that is a death sentence for the vast majority of people who get it. DMG refers to cancerous tumors that grow on the thalamus, brainstem ...

Analyzing stochastic cell-to-cell variability can potentially reveal causal interactions in gene regulatory networks.

Erdafitinib showed a predictable toxicity profile and early efficacy in IDH–wild-type glioma with FGFR-TACC fusions. The recommended phase 2 dose was 8 mg daily, with one grade 3 central serous ...

With a rate of mutation 35 percent higher than random chance, this previously unknown weakness could be a major vector for inherited disease.

NTRK gene family fusions occur in less than 1% of all solid tumors, but represent one of the most actionable oncogenic alterations across cancer types. Patients harboring these fusions can benefit ...

Despite decades of progress in pediatric oncology, outcomes for children with high-risk or recurrent rhabdomyosarcoma (RMS) remain discouragingly low. While some patients with intermediate-risk ...

Formation of fusion proteins. New genes are formed of two originally independent genes by chromosomal rearrangements, including translocations, insertions, deletions, duplications, and inversions.

A new paper published by researchers at Fox Chase Cancer Center highlights the case of a patient who was diagnosed with adenoid cystic carcinoma (ACC) after a molecular panel identified the presence ...

Disrupting tiny droplets that switch on cancer genes may be a strategy for treating a rare #kidneycancer known as translocation renal cell carcinoma (#tRCC), say researchers at @hopkinskimmel and ...

Table: Global Gene Fusion Testing Market (by Category), $Million, 2023-2035 Table: Global Gene Fusion Testing Market (by Technology), $Million, 2023-2035 Table ...