This study overall shows there is an interplay between the BBB and CB1 receptors on perivascular astrocytes that influences chronic stress resilience.

Discovery of dopamine receptors in overlooked brain region sheds light on complex circuitry for anxiety and depression. May 7, 2025. Born to run: just not on cocaine. Jan 16, 2019.

These receptors and the cells that express them mediate opposite approach/avoidance responses, and are differentially impacted by dopamine transmission in that region of the brain.

Mount Sinai researchers have discovered distinct roles for two dopamine receptors located on nerve cells within the portion of the brain that controls approach vs. avoidance behavior.

When dopamine binds to D1 receptors, it helps enhance signal processing in areas of the brain crucial for focus and attention. On the other hand, D2 receptors are more involved in modulating the ...

By blocking dopamine-1 receptors, ecopipam is expected to reduce the repetitive and compulsive behaviors seen in Tourette syndrome. The phase 3 D1AMOND trial (ClinicalTrials.gov Identifier: ...

Nicolas X. Tritsch, Motivating interest in D3 dopamine receptors, Nature Neuroscience (2024). DOI: 10.1038/s41593-024-01820-2. Journal information: Nature Neuroscience ...

Dopamine affects movement control, emotion regulation, and thinking skills. When dopamine levels are typical, they promote good health, while atypical levels can lead to health concerns. Learn more.

Glucagon-like peptide1 receptor (GLP-1R) agonists have been found to reduce alcohol drinking in rodents and overweight patients with alcohol use disorder (AUD). ... Indeed, alcohol-drinking male rats ...

Home Topics Drug Discovery How Dopamine Regulates Insulin Secretion through a Receptor Complex Light micrograph of human pancreas. Islands of Langerhans, Acinar Cells, and Ducts, 25x at 35mm.