Researchers have discovered that remodeling of extracellular matrix (ECM) in the hypothalamus, specifically around AgRP ...

Investigating ECM changes in the hypothalamus reveals mechanisms behind insulin resistance, offering insights into obesity ...

A mechanism for metabolic disease is traced to a defective cellular scaffolding that holds together the brain’s hunger cells.

In Type 1 diabetes (T1D), insulin-producing β-cells are killed by islet-infiltrating immune cells in a process called “insulitis”. T1D results in a critical requirement for exogenous insulin and ...