In 1977, the Nobel Prize in Physiology or Medicine was awarded to Roger Guillemin and Andrew Schally for their discovery and synthesis of gonadotropin-releasing hormone (GnRH), a key regulator of ...

Two newly developed PET imaging agents have been proven effective in identifying the histamine H3 receptor (H3R) that is highly expressed in neurological and psychiatric conditions. The novel agents ...

Alpha-2C adrenergic receptor or ADRA2C is an alpha-2 adrenergic receptor. It mediates the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. This receptor plays a ...

Department of Pathology, Washington University School of Medicine, St. Louis, Mo. beta-Adrenergic receptors play a critical role in signal transduction in the cardiovascular system. Regulation of beta ...

Association between β3-adrenergic receptor agonist use and risk of kidney cancer among patients with overactive bladder. Myung Eun Lee, Won Sik Jang, Jongchan Kim, Gwangmo Shin, Won Sik Ham Journal of ...

The following table summarizes the type of adrenergic receptors (α or β) present in different regions, the primary effect of epinephrine, the presence or absence of sympathetic adrenergic and ...

The adrenaline receptor studied is a member of the G protein-coupled receptor (GPCR) family, and this family is the target of one-third of all Food and Drug Administration (FDA)-approved drugs.

This involves the phosphorylation of SMO by the PKA/CKI, whose effects are further enhanced by a secondary action of FU. Notably, phosphorylation of the β-adrenergic receptor by the PKA has also been ...

β-adrenergic receptor subtypes in the heart. There are three subtypes of βARs present in the human heart, β1AR, β2AR, and β3AR. The healthy human heart comprises 80% β1ARs and 20% β2ARs, and lower ...

The distribution of variant p.Arg16Gly was relatively uniform among three genotypes. In contrast, genotypes CC, ... Assar AM, Yehia FE. Beta 2 adrenergic receptor genetic polymorphisms in bronchial ...