The 49ers are without Christian McCaffrey, Deebo Samuel and maybe George Kittle, while the Rams won’t have top receivers Cooper Kupp and Puka Nacua.

With stud wide receiver (and quasi-backup running back) Deebo Samuel Sr. out in Week 3, San Francisco will continue to lean on Mason in a divisional matchup against the Rams. It's a smash opportunity ...

After an encouraging performance in Week 1, the Rams (0-2) got something of a wake-up call in the 41-10 loss to the Cardinals ...

Nick Bosa had spoken to the media after the 49ers' 23-17 Week 2 loss to the Minnesota Vikings, where he explained how Fred ...

Although the famed Rams-49ers rivalry has been decidedly tilted in San Francisco’s direction in recent years, the games have ...

San Francisco 49ers defensive coordinator Nick Sorensen, offensive line/run game coordinator Chris Foerster, and quarterback ...

The retirement of Aaron Donald has shifted the landscape, pushing both the 49ers and Rams to adapt their strategies for an ...

Aaron Donald retired from the NFL after a commanding 10-year career with the Los Angeles Rams, and other NFL teams are happy ...

The 49ers will face the Rams on Sunday, for the first time since first-ballot, Deion-Sanders-Upper-Room Hall of Famer Aaron ...

San Francisco 49ers head coach Kyle Shanahan reveals how he's approaching his division rivals without one of the best players ...

"It's easy because nobody is going to do what Aaron does. He is the greatest ... stop by practice to lend his voice. Donald attended the Rams' joint practice against the Dallas Cowboys last ...

In the premier interview of the 2024 season, Goff admits that facing a Rams defense without the recently retired Aaron Donald is a better sight than with the future Hall of Famer – but it won't ...