C&EN1mon
Phase and Composition Engineering of Mn-Doped TiO
State Key Laboratory of Chemical Resource Engineering, College of Chemistry, Beijing University of Chemical Technology, Beijing 100029, P. R. China ...
Frontiers8mon
Diabetes cardiomyopathy: targeted regulation of mitochondrial dysfunction and therapeutic potential of plant secondary metabolites
Diabetic cardiomyopathy (DCM) is a specific heart condition in diabetic patients, which is a major cause of heart failure and significantly affects quality of life. DCM is manifested as abnormal ...
Frontiers2y
Stimulating myocardial pyruvate dehydrogenase activity fails to alleviate cardiac abnormalities in a mouse model of human Barth syndrome
In a murine model of BTHS involving short-hairpin RNA mediated knockdown of Tafazzin (TazKD mice), myocardial glucose oxidation rates were markedly reduced, likely secondary to an impairment in the ...
eLife4y
The NTP generating activity of pyruvate kinase II is critical for apicoplast maintenance in Plasmodium falciparum
We found that pyruvate kinase II (PyrKII) is essential for organelle maintenance, but that production of pyruvate by PyrKII is not responsible for this phenomenon. Enzymatic characterization of PyrKII ...
eLife4y
Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis
2018). However, there is no adequate in vivo model demonstrating the importance of BAT glycolysis or glucose oxidation on adaptive thermogenesis. We will address this question in vivo by blocking ...