The FDA has approved GlaxoSmithKline’s multiple myeloma drug Blenrep, a first-in-class potential blockbuster that will be used in advanced disease. Blenrep (belantamab mafodotin) has been ...

A year after GSK pulled its BCMA-targeting antibody-drug conjugate (ADC) Blenrep from the US market as a later-line therapy for multiple myeloma, there are signs that the drug may still have a ...

However, in November 2022, Blenrep was withdrawn from the U.S. market after the failure of GSK’s phase III confirmatory study, DREAMM-3, which evaluated Blenrep in patients with relapsed or ...

The trial evaluated Blenrep (belantamab mafodotin), in combination with pomalidomide plus dexamethasone (PomDex), versus a standard of care, bortezomib plus PomDex. A pre-specified interim ...

The molecule has one shape when ferrying oxygen molecules and a slightly different shape when it is not Its 10,000 atoms are assembled into four chains, each a helix with several bends.

The number of each atom collected is shown in the "Atoms Collected" area of the side panel. To create a molecule, make sure you have the right number of each atom and then select the correct “Create ...

And Blenrep is now filed with multiple regulators ... And the EMTs are certainly -- they're willing to experiment with this molecule. And we've seen, I mean, we tested it in markets like Italy ...

ATP consists of an adenosine base (blue), a ribose sugar (pink) and a phosphate chain. The high-energy phosphate bond in this phosphate chain is the key to ATP's energy storage potential. Cells ...

(B) A single glycerophospholipid molecule is composed of two major regions: a hydrophilic head (green) and hydrophobic tails (purple). (C) The subregions of a glycerophospholipid molecule ...

In the water molecule, the oxygen and hydrogen atoms share electrons in covalent bonds. There are a total of 10 protons and 10 electrons, so the water molecule is neutral. The electron cloud model ...

Show more The Earth is alive because of liquid water and the success of our human story is intimately connected to our relationship with this simple molecule. But the growth of our civilisations ...

Single Molecule Science (SMS) has emerged from developing, using and combining technologies such as super-resolution microscopy, atomic force microscopy, and optical and magnetic tweezers, alongside ...