Democratic Rep. Ruben Gallego will win a closely watched US Senate seat in Arizona, CNN projects, defeating Republican Kari Lake to become the state’s first Latino senator.

Republicans flipped Democratic-controlled Senate seats in West Virginia, Ohio, Pennsylvania and Montana. In the latter three cases, defeated Sens. Sherrod Brown, Bob Casey and Jon Tester also ran ahead of Harris but couldn’t overcome their states’ shifts toward the GOP.

The Democratic congressman had led Ms. Lake, a former television anchor and bombastic Trump ally, in most polls.