so histones bind with DNA very tightly. The basic repeating structural (and functional) unit of chromatin is the nucleosome, which contains eight histone proteins and about 146 base pairs of DNA ...

This DNA is wrapped around proteins to form chromatin, which exists in two main forms: euchromatin, where genes are active, and heterochromatin, where gene activity is suppressed. "How these two ...

To do so, they planned to stabilize proteins at their chromatin binding locations and use nucleic acid hybridization to fish out specific DNA sequences along with the bound proteins. By using enzymes ...

To fit such a long molecule within the tiny space of the nucleus, DNA bends and loops in several ways. The largest of these loops results from the helical coiling of chromatin (the thick line in ...

In eukaryotes, DNA is tightly wound into a complex called chromatin. Thanks to the process of chromatin remodeling, this complex can be "opened" so that specific genes are expressed. Various ...

Researchers at the Paul Scherrer Institute PSI have developed an AI that could open up a new, cost-effective approach to ...

DNA might be too small to see with the unaided eye, but it packs our cells in shocking quantities: More than six and a half ...

In the cell nucleus, DNA loops around proteins and together they form a thick fiber called chromatin. Genes at the heart of a tight chromatin coil are hard to reach, and thus, essentially inactive.

In the earliest hours after fertilization, an embryo takes its first steps toward becoming a living organism by shedding ...

A team of researchers led by Prof. XIAO Jun from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences has discovered a new way in which temperature can ...

A small but powerful clinical trial reveals that resveratrol and copper can reduce tumor growth, restore immune function, and ...