Researchers at the Paul Scherrer Institute PSI have developed an AI that could open up a new, cost-effective approach to ...

so histones bind with DNA very tightly. The basic repeating structural (and functional) unit of chromatin is the nucleosome, which contains eight histone proteins and about 146 base pairs of DNA ...

To do so, they planned to stabilize proteins at their chromatin binding locations and use nucleic acid hybridization to fish out specific DNA sequences along with the bound proteins. By using enzymes ...

DNA might be too small to see with the unaided eye, but it packs our cells in shocking quantities: More than six and a half ...

To fit such a long molecule within the tiny space of the nucleus, DNA bends and loops in several ways. The largest of these loops results from the helical coiling of chromatin (the thick line in ...

In eukaryotes, DNA is tightly wound into a complex called chromatin. Thanks to the process of chromatin remodeling, this complex can be "opened" so that specific genes are expressed. Various ...

In the cell nucleus, DNA loops around proteins and together they form a thick fiber called chromatin. Genes at the heart of a tight chromatin coil are hard to reach, and thus, essentially inactive.

In eukaryotes, genomic DNA is stored in the nucleus as nucleosomes, interacting with a set of proteins, forming a molecular complex called chromatin. The proper folding of the chromatin structure ...

Researchers use generative AI to design synthetic enhancers that can effectively control gene expression in healthy mammalian cells.

A small but powerful clinical trial reveals that resveratrol and copper can reduce tumor growth, restore immune function, and ...