A small-molecule compound named TAC has been identified that reawakens the catalytic subunit of telomerase (TERT) in somatic cells and, in doing so, stalls multiple hallmarks of natural aging without ...
Telomerase reverse transcriptase (TERT), an enzyme associated with nearly all malignant human cancers, is even more diverse and unconventional than previously realized, new CU Boulder research finds.
Small molecule restores TERT levels, reversing hallmarks of aging A high-throughput screen of over 650,000 compounds identified a small-molecule TERT activating compound (TAC) that epigenetically ...
Fusobacterium nucleatum to promote esophageal squamous cell carcinoma progression via CCL20/CCR6-mediated migration of macrophages to the tumour micro environment. This is an ASCO Meeting Abstract ...
The shortening of human telomeres – caps that protect our chromosomes from deterioration – has been associated with aging and disease. Now, researchers from the Stanford University School of Medicine, ...
Crossbow Therapeutics Inc. has provided details on the preclinical characterization for the telomerase reverse transcriptase (TERT)-targeting T-cell engager CBX-663.
In pre-clinical trials, a small molecule effectively regrew neurons, reduced inflammation, and improved memory, speed, coordination, grip strength, and more. The finding could have a profound impact ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback