Figure 1: αK40 acetylation impairs microtubule nucleation and accelerates depolymerization. No cell lines were used in this study. Bovine brain tubulin was purified as previously described 39. Briefly ...
Figure 1: The tubulin–colchicine:RB3-SLD complex. A comparison of the structure of tubulin heterodimers in T2R (which is similar to that of GDP–tubulin in curved protofilaments 11) and in straight ...
The tubulin family of proteins are vital components of the eukaryotic cytoskeleton and are the main constituent of microtubules in living cells. The tubulin proteins α- and β polymerize into long ...
Microtubules are cell constituents that display several astounding properties and a unique pattern of behavior during the cell cycle. Microtubules are regulated by several proteins and complexes, and ...
Constructed with tubulin heterodimers connected into a hollow cylinder, the microtubule, an essential component of the ...
PURPOSE: The mechanisms that cause chemoresistance in non–small-cell lung cancer (NSCLC) patients have yet to be clearly elucidated. Paclitaxel is a tubulin-disrupting agent that binds preferentially ...
Influence of CHAARTED, STAMPEDE, and LATITUDE eligibility criteria on utilization of abiraterone (A) and docetaxel (D). This is an ASCO Meeting Abstract from the 2018 Genitourinary Cancers Symposium.
Scientists have identified tubulin structures in primitive Asgard archea that may have been the precursor of our own cellular skeletons. In 2010, biologists made a shocking discovery. Living in the ...
Hubei Polytechnic University (Huangshi, China) scientists and collaborators aimed to develop potential tubulin polymerization ...
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