The Tennessee Titans and Indianapolis Colts play on Sunday, Oct. 26, 2025 at Lucas Oil Stadium. The Titans are 1-6 and the Colts are 6-1.

Colts defensive end Tyquan Lewis ruled out for Sunday's game against Titans with groin injury. Indy makes more roster moves.

Here's what you need to know about the Titans' next game and opponent: The Indianapolis Colts ' hot start has continued with wins over the Raiders and Cardinals since the Week 3 game in Nashville. Daniel Jones currently has career highs in yards per attempt and passer rating this year along with 12 total touchdowns through six games.

The Patriots and Titans play Sunday in Week 7 of the 2025 NFL season. Patriots wide receiver Stefon Diggs and edge rusher Harold Landry III are both questionable to play in the game, while Titans wide receiver Calvin Ridley has been ruled out.

Following Friday's practice, Indianapolis Colts head coach Shane Steiche announced that wide receiver Josh Downs is available for the team's Week 8 game with Tennessee. Downs entered concussion protocol after the Colts ' Week 6 game against the Arizona Cardinals. After not practicing last week, he then did not play this past Sunday in LA.

The NFL season continues with the Tennessee Titans hosting the New England Patriots Sunday. Start time, where to watch, streaming and NFL schedule.

New England Patriots defensive end K'Lavon Chaisson was named the AFC Defensive Player of the Week for his performance against the Titans.

Questions loom about WR Calvin Ridley, DT Jeffery Simmons and CB L'Jarius Sneed as the Tennessee Titans ready themselves for the Indianapolis Colts.