More than one hundred different mutations in the gene encoding rhodopsin are associated with a group of retinal degenerations including retinitis pigmentosa, congenital stationary night blindness ...

At the heart of this issue is the protein rhodopsin, which, due to genetic mutations, often misfolds. This misfolding ...

Investigators from the University of Pennsylvania and Cornell University provide evidence for retinal injury caused by moderate light exposure in dogs with a mutation in the rhodopsin gene. Since ...

In a study on inherited retinal degeneration, researchers developed a single gene therapy vector that prevented photoreceptor cell death and vision loss in a canine model of autosomal dominant ...

More than 150 different mutations in the light-sensing molecule rhodopsin can cause retinitis pigmentosa, characterized by a progressive loss of night and peripheral vision. A team from the ...

More than 150 different mutations in the light-sensing molecule rhodopsin can cause retinitis pigmentosa, characterized by a progressive loss of night and peripheral vision. A team has now ...

A lmost 200 million people worldwide suffer from macular degeneration, a condition that affects central vision and can result in near blindness. 1 Although most forms of macular degeneration affect ...

“We now report that retinal degeneration in mice can be significantly delayed by ... Applying this strategy to mice bearing one copy of the P23H rhodopsin mutant, a mutation frequently ...