Voretigene neparvovec-rzyl (VN) therapy partially restored electroretinogram (ERG) responses in some RPE65-related retinopathy patients, with sustained improvements over several years. The study ...

CHICAGO — Children with a rare, inherited retinal disorder who were treated with the first Food and Drug Administration-approved gene therapy had noticeable improvements in vision that may be related ...

Gene therapy with voretigene neparvovec-rzyl partially restores geniculostriate pathway function in LCA2 patients, improving visual processing. Initial LCA2 pathology shifts visual processing from the ...

PDE6A-associated RP, a rare form of inherited retinal disease (IRD), is characterized by nyctalopia, visual field defects, and significant loss of visual acuity (VA). The disease primarily affects the ...

Get a closer look at the biotech ophthalmology landscape to discover exactly how companies are approaching the treatment of eye diseases.

A gene therapy that significantly improves vision in a form of Leber congenital amaurosis (LCA) does not slow global degeneration of photoreceptors, according to a report published online January 22 ...

Scientists at Oregon Health & Science University's Casey Eye Institute and Baylor College of Medicine's Cullen Eye Institute published findings from a two-year Phase I clinical trial in the journal ...

Retinal diseases are at the forefront of a quiet revolution in the realm of ophthalmology. Gene therapy, once a distant dream, is now emerging as a beacon of hope for millions affected by these ...

New AAV therapy for retinitis pigmentosa completes Phase I/II dosing, aiming to protect cones and slow vision loss; first ...

BOSTON (Reuters) - A year after receiving gene therapy for a condition that causes total blindness by age 30, three people continue to see better and one has improved enough to read the digital ...