Receptors for ATP and ADP and adenosine exert various effects. ... Purinergic signaling is an important link among platelet activation, vascular thrombosis, and inflammation.

P2X7 is one of seven purinergic receptors activated by ATP. The receptor has both ion channel and pore-forming activity, though how these two are related is not clear, Williams told ARF. It was also ...

Purinergic receptors sit on the plasma membrane and are activated by ATP or its breakdown products ADP, AMP, and adenosine. In addition to playing a role in cell metabolism, these molecules signal ...

A recent study analyzed the role of purinergic receptor P2X4 in microglia/macrophages during autoimmune inflammation, finding that P2X4 receptors modulate microglia/macrophage inflammatory ...

Euroscreen SA has announced that it was awarded a US patent that covers the use of a G-Protein-Coupled Receptor (GPCR) known as the human P2Y11 receptor. The new Euroscreen's US patent (7,264,940) ...