Scientists are investigating the previously largely unknown biosynthetic pathway that leads to the formation of cardenolides in plants. In a new study, they present two enzymes from the CYP87A ...

Pregnenolone sulfate, an endogenous neurosteroid in the central nervous system, is a positive allosteric modulator of the NMDA receptor, and plays a role in the modulation of learning and memory.

The Neuroactive Steroid Pregnenolone Sulfate Stimulates Trafficking of Functional NMDA Receptors to the Cell Surface via a Non-Canonical G-Protein and Ca Dependent Mechanism. Molecular ...