The frontal lobe is divided into three main areas characterized by their function and anatomy: prefrontal cortex, primary motor cortex, ... Ventromedial Orbitofrontal Cortex Syndromes.

Recent work in a number of species has emphasized the role of orbitofrontal cortex in value-based decision-making. However, discrepancies have arisen when comparing the findings from animal models ...

A new study links anxiety, a brain structure called the orbitofrontal cortex, and optimism, finding that healthy adults who have larger OFCs tend to be more optimistic and less anxious.

More information: Wenhui Zong et al, Hippocampal output suppresses orbitofrontal cortex schema cell formation, Nature Neuroscience (2025). DOI: 10.1038/s41593-025-01928-z.

Orbitofrontal cortex modulates auditory cortical sensitivity and sound perception in Mongolian gerbils. Current Biology , 2024; DOI: 10.1016/j.cub.2024.06.036 Cite This Page : ...

A new study linked chronic pain to activity in the orbitofrontal cortex, an area involved in emotion regulation, self-evaluation and decision making. By Priyanka Runwal Researchers have for the ...

A higher burden of NLE, a thicker orbitofrontal cortex at the age of 14 years, and an accelerated orbitofrontal cortex thinning across adolescence predicted young adults' depressive symptoms.

A new study links anxiety, a brain structure called the orbitofrontal cortex, and optimism, finding that healthy adults who have larger OFCs tend to be more optimistic and less anxious.

The changes in the orbitofrontal cortex of the marijuana users could be taking place as a result of the brain cutting back on its receptors for THC, the main psychoactive agent in the marijuana ...

A new study links anxiety, a brain structure called the orbitofrontal cortex (OFC), and optimism, finding that healthy adults who have larger OFCs tend to be more optimistic and less anxious.