Flipping the switch on fewer than 500 neurons dramatically reduces the alcohol consumption of mice. This novel finding could ...

Scientists have long known that hope aids behavior. Recent research shows that individual differences in spontaneous brain ...

Despite the profound human, social and economic costs of alcohol abuse, existing treatments have failed to provide meaningful ...

Reciprocal connections between the orbitofrontal cortex and the basolateral nucleus of the amygdala may provide a critical circuit for the learning that underlies goal-directed behavior. We ...

The orbitofrontal cortex (OFC) is a region in the frontal lobe of the brain known to be involved in decision-making and information processing. The lateral part of this brain region, known as the ...

Life can be tricky. We have so many decisions to make. It's a good thing we have an orbitofrontal cortex and hippocampus to help us. These areas of the brain work together to help us sort through ...

Scientists describe the orbitofrontal cortex as a key area for mapping possible behaviors in a particular situation and as a hub for decision-making, especially about social behavior.

A new study linked chronic pain to activity in the orbitofrontal cortex, an area involved in emotion regulation, self-evaluation and decision making. By Priyanka Runwal Researchers have for the ...

A higher burden of NLE, a thicker orbitofrontal cortex at the age of 14 years, and an accelerated orbitofrontal cortex thinning across adolescence predicted young adults' depressive symptoms.

Overexpression of Shisa7 in the orbitofrontal cortex in drug-free rats induced comparable up and down changes in gene expression as that induced by the self-administration of heroin. The ...