Figure 1: Histone chaperones are key regulators of replication-coupled and replication-independent nucleosome assembly. Figure 2: H3–H4 histone chaperones bind a H3–H4 dimer or a (H3–H4) 2 ...

Histone proteins, for example, are ... (ROIS), used single-nucleosome imaging to reveal the factors that contribute to the organization and compaction of chromosomes during mitosis in living cells ...

Recent data suggest that histone modifications have a direct effect on nucleosomal architecture. Acetylation, methylation, phosphorylation and citrullination of the histone core may influence ...

Researchers recently tracked small stretches of DNA wound around histone proteins, called nucleosomes, to better characterize nucleosome behavior during cell division. AZoLifeSciences.

For example, if a histone protein has 10 modification sites, ... so another goal in cracking the code is to better understand the interplay between the nucleosome proteins and the nearby genes.

DNA wraps around these histone proteins to form nucleosomes, which help condense nearly six feet of human genomic DNA into a nucleus only 10 micrometers (1 x 10-6 m) across.

Human PR-DUB complex is composed of ubiquitin C-terminal hydrolase BAP1 (BRCA1 associated protein 1) ... "It interacts with histone H3-H4 and DNA next to the nucleosome dyad." ...

Histone proteins at the core of nucleosomes and their tails exert control over the exposure of genes for ... the terminal regions of the core proteins -- play a crucial role in nucleosome stability.

Histone-modifying proteins, not histones, remain associated with DNA through replication Date: August 23, 2012 Source: Thomas Jefferson University ...

The Nucleosome Untangled. FEATUREEpigenetics All art: Rick Contreras All photography: ... This regulation takes place in the context of the histone proteins. Two each of the four standard histones - ...

Histone-modifying proteins, not histones, remain associated with DNA through replication Thomas Jefferson University team shifts a longstanding paradigm for epigenetic markers ...

To package it all into a tiny nucleus, the DNA strand is tightly wrapped around a core of histone proteins in repeating units—each unit known as a nucleosome.