Rodent medial prefrontal cortex is not crucial for an active place avoidance task requiring cognitive control evidenced by hippocampal activity that purposefully alternates between task-relevant and ...

For instance, past studies have found that the ventromedial prefrontal cortex, which takes on the same role as the mouse mPFC in the human brain, is hyper-activated in people diagnosed with ...

Recreational drug use during adolescence may disrupt development of an understudied part of the prefrontal cortex, according to a study of male mice published in eNeuro.

Faulty wiring of the prefrontal cortex during development leads to abnormal brain activity and cognitive impairments related to mental illness, according to a mouse study published in JNeurosci.

Thirty-three of the 121 participants had an injury to the medial prefrontal cortex, 17 had an injury elsewhere in the brain, while 71 had no brain damage but were of the same age as the others.