Histone H3 is specifically phosphorylated during both mitosis and meiosis in patterns that are specifically coordinated in both space and time. Histone H3 phosphorylation may initiate at different ...

Programmable human histone phosphorylation and gene activation using a CRISPR/Cas9-based chromatin kinase. Nature Communications , 2021; 12 (1) DOI: 10.1038/s41467-021-21188-2 Cite This Page : ...

It has been proposed that acetylation of the amino-terminal tails of the core histones within the nucleosome particle is critical for activating transcription. In the December Genes and Development, ...

Histone H1 phosphorylation is associated with transcription by RNA polymerases I and II. The Journal of Cell Biology , 2010; 189 (3): 407 DOI: 10.1083/jcb.201001148 Cite This Page : ...

The discovery of this demethylase supports the long-held supposition that histone methylation is reversible, just as histone phosphorylation and acetylation are, Shilatifard points out.

Histone phosphorylation at H2A on T120 and H3 at S10 are required for the compaction of chromatin and regulation of its structure and function during mitosis. Histone Modification Play.

No other epigenome editing technique has enabled site-specific control over histone phosphorylation, he said. The programmable Rice tool, called dCas9-dMSK1, fuses a deactivated "dCas9" protein ...

Graphical abstract from “The fork protection complex promotes parental histone recycling and epigenetic memory” [Charlton et al. Cell 2024; DOI: 10.1016/j.cell.2024.07.017].