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Less histone H2A.Z at promoters after DNA replication. Given the importance of understanding how the chromatin structure of an active gene is inherited during the cell cycle, we determined how ...
The team reconstituted this complex using only CENP-A, histone H4 proteins, and DNA fragments; they intentionally excluded histones H2A and H2B, as these were known to be reduced in yeast centromeres.
Histone phosphorylation at H2A on T120 and H3 at S10 are required for the compaction of chromatin and regulation of its structure and function during mitosis. Histone Modification Play References ...
The resulting DNA-histone structure, collectively called chromatin, regulates DNA stability and gene expression. It is not surprising, therefore, that histone function is highly ... Domain structure ...
The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the ...
The basic unit of chromatin is the nucleosome, which is composed of 147 base pairs of DNA wrapped around 2 copies each of 4 histone proteins namely H2A, H2B, H3, and H4 (histone octamer).
So-called histone methyltransferases "also methylate a broad range of other protein substrates," Coonrod explains, noting that arginine methylation is a particularly widespread modification.