Hosted on MSN2mon
Cancer cells may be using lipids to hide from the immune system
Cancer cells seldom start off stealthy ... the team turned to an FDA-approved drug used to treat Gaucher disease—a genetic disorder characterized by an impaired ability to break down lipids.
Hosted on MSN28d
Inability of cells to recycle fats can spell disease: Study reveals how a protein helps transport fats out of lysosomes
Diseases like Gaucher disease, Tay-Sachs disease, Niemann-Pick disease, and Pompe disease result from waste buildup in cells, leading to serious health issues. Dysfunctions of the lysosomal ...
The Harvard Crimson6y
Dr. L. Lahut Uzman, Medical Investigator Here, Dies at Age of 39
Dr. Uzman showed that analysis of fat-like lipid, kerasin, as performed over the previous 40 years, was not enough to explain the peculiar Gaucher cells, sign of the disease. It is also necessary ...
Science Daily1mon
Inability of cells to recycle fats can spell disease
Diseases like Gaucher disease, Tay-Sachs disease, Niemann-Pick disease, and Pompe disease result from waste buildup in cells, leading to serious health issues. Dysfunctions of the lysosomal ...
News Medical1mon
Protein identified as key to preventing fat build-up and related diseases
Diseases like Gaucher disease, Tay-Sachs disease, Niemann-Pick disease, and Pompe disease result from waste buildup in cells, leading to serious health issues. Dysfunctions of the lysosomal ...
Nature22d
Pfizer stakes a claim in plant cell–made biopharmaceuticals
Gaucher's disease is the most prevalent among ... “This was a unique opportunity to take advantage of their plant cell technology platform with this lead drug to perhaps provide a more cost ...
Nature2mon
Virus stalls Genzyme plant
Genzyme anticipates supply constraints of Cerezyme (imiglucerase), a treatment for Gaucher disease, and Fabrazyme (agalsidase beta), used to treat Fabry disease, while the facility shuts down for ...