A pioneering study has revealed that increased stiffness in the extracellular matrix (ECM) of spinal discs impairs energy production in nucleus pulposus cells (NPCs), a key factor in intervertebral ...
This study fills the gap by demonstrating that PAK5 promotes ... leading to enhanced glycolysis and endometriotic cell growth. Conversely, PAK5 knockdown reduced PKM2 levels and cellular ...