Promising pipeline dopamine receptor antagonists such as ONC206, Ecopipam, LYN-005, Mesdopetam, NG101, Naronapride, ENX-104, and others are under different phases of dopamine receptor antagonists ...

Topline data were announced from a phase 3 trial evaluating ecopipam, a dopamine-1 receptor antagonist, in pediatric and adult patients with Tourette syndrome.

Dopamine antagonists that act on dopamine receptors in the gastrointestinal tract may be used to treat nausea, or as anti-emetics to stop vomiting. Dopamine antagonist drugs include: ...

Current treatments for dopamine-related conditions use agents that can either block or enhance dopamine signaling, such as stimulants used to treat attention-deficit/hyperactivity disorder, including ...

(HealthDay)—Use of dopaminergic antagonists and agonists can affect blood pressure (BP), according to a review published online Nov. 8 in the Journal of Clinical Pharmacy and Therapeutics.

In the current study, the researchers targeted KOR, a subtype of opioid receptor that when activated can decrease synaptic dopamine levels by decreasing dopamine release and increasing the ...

D1 receptors and D4 receptors are responsible for the cognitive-enhancing effects of dopamine. Some of the antipsychotic medications used in conditions like schizophrenia act as dopamine antagonists.