A chromosomal abnormality occurs when there is an incorrect number of chromosomes, an incorrect amount of DNA within a chromosome, or chromosomes that are structurally flawed.

Although these anomalies generally consisted of trisomy of a whole chromosome, some were due to a structural variation that included both de novo and familial anomalies. The abnormalities of ...

Chromosomes at the nuclear periphery are prone to mis-segregation. Skip to main content. Thank you for visiting nature.com. ... Location in the nucleus foretells chromosome anomalies.

Only in the mother of Case 1 was an abnormality found. She had 47 chromosomes, the extra one being in the 6–12 (C) group. Many of the cells from her buccal smear contained 2 Barr bodies, ...

Unexpected pregnancy loss can be a traumatic experience for fertile couples. The aim of the study was to assess the nature and type of chromosomal variants involved in early and late pregnancy loss ...

Most humans have 23 pairs of chromosomes. One of these pairs is the sex chromosomes. Unless someone has a chromosome abnormality, it usually consists of either two X chromosomes or an X and a Y.

The foetus' DNA is then isolated, sequenced and analysed to see if it carries a chromosome anomaly, which is the case in about 50 to 60 percent of miscarriages.