Both Sca-1 and CD86 are expressed on hematopoietic stem progenitor cells (HSPCs) at steady state. However, under biological stresses, such as infection and inflammation, myeloid progenitors acquire ...
Blockade of the CD40–CD40L and CD80/CD86–CD28 costimulatory pathways represents a strategy to inhibit the immune response against Ad vectors designed for gene therapy applications. Since most previous ...
A broad range of leukocyte cell surface antigens are released as soluble forms, many of which have agonistic, antagonistic or independent biological effects relative to their membrane bound ...
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