Upon induction of maturation in vivo, DCs upregulate CCR7, a chemokine receptor that drives DCs to migrate to the lymphatics. 13 Once antigen-loaded DCs arrive at the local lymphatic organ, they ...
On September 22, 2025, Imunon, Inc. (NASDAQ:IMNN) announced that new translational data from the Phase 2 OVATION 2 trial of IMNN-001 was presented at the American Association for Cancer Research (AACR ...
Dendritic cells (DCs) link innate and adaptive immunity and use a host of innate immune and inflammatory receptors to respond to pathogens and inflammatory stimuli. Although DC maturation via ...
Dendritic cells (DCs) are strategically positioned to take up antigens and initiate adaptive immunity. One DC subset expresses CD8αα in mice and is specialized to capture dying cells and process ...
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