Although membrane blebbing is a characteristic morphological change associated with apoptosis, little is known about the mechanisms underlying this process. New research has identified the Rho GTPase ...

Existing microscopy-based methods of detecting apoptosis, such as TUNEL (terminal deoxynucleotidyl transferase dUTP nick-end labeling), have limited quantitative capabilities due to insufficient ...

The terminal stages of programmed cell death (apoptosis) can be identified by the condensation of chromatin and fragmentation of the genomic DNA, alongside blebbing of the membrane. As apoptosis ...

Blebbing occurs when a call’s plasma membrane separates from its cytoskeleton and forms a membrane bulge filled with cytoplasm. This bulge will eventually separate from the cell, taking part of the ...