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Tridecanoic acid (C13) is a rare, odd-chain saturated fatty acid produced mainly by gut and rumen microbes, entering ...
Carnitine palmitoyltransferase II (CPT2) deficiency is a rare autosomal recessive disorder of mitochondrial fatty acid oxidation. The most common form of this disorder is characterized by muscle ...
As early as some 40 years ago, pharmaceutical researchers therefore developed a corresponding inhibitor, etomoxir. It binds to enzymes required for beta-oxidation, bringing it to a halt.
Baruteau J, Sachs P, Broue P, et al. Clinical and biological features at diagnosis in mitochondrial fatty acid beta-oxidation defects: a French pediatric study of 187 patients.
CPT1 is responsible for the formation of acylcarnitine from ACADL (acyl-coenzyme A dehydrogenase, long chain), which is responsible for beta-oxidation of fatty acids within the mitochondria.
Pyruvate oxidation is critical determinant of pancreatic islet number, beta-cell mass. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2014 / 08 / 140805150851.htm ...
Baruteau J, Sachs P, Broue P, et al. Clinical and biological features at diagnosis in mitochondrial fatty acid beta-oxidation defects: a French pediatric study of 187 patients.
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