Basophils provide frontline defense against infection and are involved in processes like inflammation and allergies. ... Often, basopenia is only one symptom or lab abnormality out of several.

While not a common finding, abnormalities in the numbers of circulating basophils, be it an increase (basophilia) or decrease (basopenia) can be indicative of a variety of underlying conditions.

Basophils are a type of white blood cell. Although they’re produced in the bone marrow, they’re found in many tissues throughout your body. Their normal blood range should be under 300 per ...

Basophils are white blood cells that the bone marrow makes. They play a role in a healthy immune system. Having more or less basophils than usual may be a sign of inflammation, hyperthyroidism, or ...

A positive basophil activation test result may be a prognostic factor of pediatric chronic urticaria resolution, according to new research published in JAMA Dermatology.Because the etiology of ...

By Richard P. Grant Basophil Roles Dr. David Phillips/Visuals Unlimited, Inc. The paper C. Ohnmacht et al., “Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths ...

Basophils from each strain were stimulated with antigen combined with IgE, IL-33, or lipopolysaccharide (LPS). We measured ...

“Basophil count was significantly increased in nasal polyps of the ECRS patients,” the researchers wrote. “Conversely, compared with the non-ECRS patients, CD4 + and CD8 + T-cell levels were ...

In mice whose basophils were unable to produce IL-4, protease treatment did not cause lung inflammation, suggesting that basophil-derived IL-4 could be the main driver of protease-allergen-induced ...

Basophils were deemed critical in allergic response and parasite removal, but their precise role has been controversial. David Vöhringer, now at Universitätsklinikum Erlangen, found that basophils are ...