Understanding the interplay between T cells and B cells is pivotal to delineating both protective immunity and the pathogenesis of autoimmune diseases. Central to this dynamic are specialised CD4 ...

Researchers use targeted lipid nanoparticles loaded with mRNA to reprogram T cells to fight autoimmune diseases ...

A research team has discovered a previously unknown mechanism that could explain why many patients with aggressive B-cell ...

Capstan Therapeutics scientists demonstrate that lipid nanoparticles can engineer CAR T cells within the body without ...

In the largest study of its kind, researchers from The University of Texas MD Anderson Cancer Center identified three ...

For many people, B-cell lymphomas don’t need treatment right away. ... Different types of targeted therapy focus on other interactions between cancer cells. B-Cell Lymphoma Survival Rate.

B) Application of Granzyme B activity assay to CAR-T cell/target cell interaction. Left: CAR-T cell and nontarget cell, no CAR mediated signal, no Granzyme B release, 5-FAM fluorescence quenched.

Chimeric antigen receptor (CAR) T cells targeting CD19 have transformed the treatment of B-cell cancers, but many patients do not have long-term remission. We designed an anti-CD19 enhanced (armore ...

More information: Jonas Nørskov Søndergaard et al, Single cell suppression profiling of human regulatory T cells, Nature Communications (2025). DOI: 10.1038/s41467-024-55746-1 Provided by Osaka ...

On February 13, Allogene Therapeutics published new long-term follow-up data on cemacabtagene ansegedleucel, showing the investigative allogeneic chimeric antigen receptor (CAR) T-cell therapy ...

B cells are a type of white blood cell. They make antibodies -- proteins that fight viruses and bacteria. B cells normally can’t cross from your blood into your brain or spinal cord. If you have ...