Noradrenaline enhances vision through beta-adrenergic receptors. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2017 / 02 / 170209090943.htm ...

“ATR-258, a synthetic small molecule, has favourable pharmacokinetics and in Phase 1 clinical trials has been administered just once a day as a capsule, making it a straightforward, patient-friendly ...

In their study, the researchers focused on the β1-adrenergic receptor, a GPCR that plays a key role in the cardiovascular system and is targeted by beta-blockers.

Known as the the B-adrenergic receptor, it is an essential player in the regulation of heart rate and blood pressure. In the 1980’s, Kobilka, now at Stanford University, ...

This article reviews the current state of knowledge and understanding of the genetic variation present in the three human beta-adrenergic receptor genes.

Here we show in atomistic detail how the human β2-adrenergic receptor (β2AR) – a prototypical G protein-coupled receptor – is modulated by cholesterol in an allosteric fashion. Extensive atomistic ...

Based on the structure of these compounds and the characterization of the structural interaction between ‘9087 and the α 2a-adrenergic receptor, the researchers further developed additional ...

Here we explore this issue through atomistic MD simulations (∼5 μs in total), focusing on the β2-adrenergic receptor (β2AR) that is one of the most studied members of the G-protein coupled receptor ...

The addition of β-adrenergic antagonists to the treatment regimen for heart failure has validated the neurohormonal hypothesis and provided much-improved outcomes. This benefit had been in ...

Although beta-adrenergic–receptor antagonists reduce morbidity and mortality in patients with mild-to-moderate chronic heart failure, their effect on survival in patients with more advanced ...