After an initial treatment response, most ovarian cancers recur because of drug-resistant cell populations. Blood-based tracking, used to monitor clonal evolution in 18 patients, shows that ...

Cancer does not develop overnight. It can take decades for cancer-promoting changes in the genome to eventually lead to the formation of a malignant tumor. Researchers at the German Cancer Research ...

Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related condition associated with increased mortality among patients with cancer. CHIP mutations with high variant-allele frequencies ...

In a recent study published in Nature, researchers investigate the spatial organization of cancer cells and the tumor microenvironment by analyzing over one hundred tumor sections across six types of ...

Researchers have developed a three-dimensional mathematical model of prostate cancer. The model depicts various processes, including tumour growth, genetic evolution and tumour cell competition.