In their Week 11 matchup on Sunday at 4:05 PM ET, RB Isaac Guerendo and the San Francisco 49ers square off against the ...

ANALYSIS: San Francisco 49ers running back Isaac Guerendo has barely seen the field as a rookie. He is the RB63 for the year, ...

Guerendo had one carry for zero yards in Sunday's 23-20 win over Tampa Bay. With star tailback Christian McCaffrey (Achilles) returning to action and backup Jordan Mason (shoulder) healthy, Guerendo ...

San Francisco 49ers running back Christian McCaffrey is set to make his season debut on Sunday against the Tampa Bay ...

Since joining the 49ers, Isaac Guerendo's rise to significant snaps came in the wake of injuries to star running backs Christian McCaffrey, Elijah ...

San Francisco 49ers running back Isaac Guerendo has looked like one of the most explosive backs in the NFL in his limited ...

San Francisco 49ers running back Isaac Guerendo joined the 49ers "You've Got Mail" podcast presented by Delta Dental to ...

There's no such thing as having too many running backs. Just ask the San Francisco 49ers. Jordan Mason, who is starting in ...

San Francisco 49ers running back Isaac Guerendo joined the 49ers "You've Got Mail" podcast presented by Delta Dental to discuss his journey to the pros, the early contributions of the rookie class and ...

Matthew Berry, Jay Croucher, and Connor Rogers highlight their top running back waiver wire adds Week 10, including Jaylen ...

In Week 10, running back Isaac Guerendo and the San Francisco 49ers' rushing attack will square off against the Tampa Bay ...