Homepage | ADC Fetal & Neonatal Edition
WEB2 days ago · s an edition of ADC from BMJ and RCPCH, publishing perinatal & neonatal medicine research and reviews. Archives of Disease in Childhood: Fetal & Neonatal is a Plan S compliant Transformative Journal. Archives of Disease in Childhood is led by Dr Nick Brown, clinician, epidemiologist and international child health expert.
Haemolytic disease of the newborn - ADC Fetal & Neonatal Edition
WEBThe changing management of haemolytic disease of the newborn is reviewed In the space of most paediatricians working lifetime, the spectrum of haemolytic disease of the newborn (HDN) has changed beyond recognition. Thirty years ago, HDN was almost synonymous with Rh D allo-immunisation and was a common neonatal problem. It was usually unmodified by antenatal therapy and caused overt fetal or ...
Implementation of this Framework for Practice - ADC Fetal
WEBDefinitions. In the UK, a stillbirth is legally defined as the birth of a baby with no signs of life at, or after, 24 completed weeks of gestation.. For consistency, we have used the term ‘fetus’ to describe the baby before birth, and ‘baby’ after birth.Within the document, ‘parents’ refers to the mother and her partner. We have used the terms ‘active care (survival focused ...
Authors | ADC Fetal & Neonatal Edition
WEBWhen publishing in ADC: Fetal & Neonatal, authors choose between three licence types – exclusive licence granted to BMJ, CC-BY-NC and CC-BY (Creative Commons open access licences require payment of an article processing charge).As an author you may wish to post your article in an institutional or subject repository, or on a …
What’s new in the management of neonatal early- onset sepsis?
WEBa single CRP value for proven sepsis was 64% (95% CI 53 to. 59) with a positive predictive value of only 14% (95% CI 11 to. 17).45 However, if serial CRP values remain normal, there is a low likelihood of infection with a negative predictive value of nearly 100%46 The 2021 NICE guidelines recommend use of.
What’s new in the management of neonatal early-onset sepsis?
WEBThe expert guidelines highlighted in this review provide an evidence-based framework for approaching at-risk infants and allow for a more limited and standardised approach to antibiotic use. While these guidelines have significantly reduced antibiotic utilisation worldwide, optimally each unit would individualise their approach to early onset sepsis (EOS) based on the neonatal population they ...
Management and investigation of neonatal encephalopathy: 2017 …
WEBThis review discusses an approach to determining the cause of neonatal encephalopathy, as well as current evidence on resuscitation and subsequent management of hypoxic-ischaemic encephalopathy (HIE). Encephalopathy in neonates can be due to varied aetiologies in addition to hypoxic-ischaemia. A combination of careful history, examination and the judicious use of investigations can help ...
Trends in the incidence and management of hypoxic-ischaemic ...
WEBObjective Hypoxic-ischaemic encephalopathy (HIE) remains a leading cause of neonatal mortality and neurodisability. We aimed to determine the incidence of HIE and management patterns against national guidelines. Design Retrospective cohort study using the National Neonatal Research Database. Setting Neonatal units in England and Wales. Patients Infants 34–42 weeks gestational age (GA) with a ...
Understanding the principle biophysics concepts of pulmonary …
WEBPulmonary surfactant (PS) is a lipid-protein complex essential to stabilise the delicate structure of mammalian alveoli along with successive compression-expansion respiratory cycles. To do so, surfactant reduces dramatically surface tension at the air-liquid interface, an activity that depends critically on a proper lipid composition and the presence of some specific surfactant proteins. Lack ...
Causes and consequences of fetal acidosis - ADC Fetal & Neonatal …
WEBThe fetus depends on the mother for placental exchange of oxygen and carbon dioxide. This in turn relies on adequate maternal blood gas concentrations, uterine blood supply, placental transfer and fetal gas transport. Disruption of any of these can cause fetal hypoxia, which, despite compensatory mechanisms, may lead to acidosis. When severe and acute (lasting hours), but especially if ...
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