SARS-CoV-2 Omicron variant: recent progress and future …
WEBApr 28, 2022 · The Omicron variant is the most mutated SARS-CoV-2 variant, and its high transmissibility and immune evasion ability have raised global concerns. Owing to its enhanced transmissibility,...
A Detailed Overview of SARS-CoV-2 Omicron: Its Sub-Variants, …
WEBJan 5, 2023 · Omicron has many mutations in its viral genome. According to the reports published on April 2022 by the WHO, five sub-variants of the Omicron variant have been detected. They are BA.1, BA.2, BA.3, BA.4, and BA.5. These mutations have been prevalent worldwide in different quantities (Figure 3 A) [30].
Immunological and metabolic characteristics of the Omicron …
WEBJan 21, 2023 · The Omicron variants of SARS-CoV-2, primarily authenticated in November 2021 in South Africa, has initiated the 5th wave of global pandemics. Here, we systemically examined immunological and...
Emergence of SARS-CoV-2 Omicron (B.1.1.529) variant, salient …
WEBJan 29, 2022 · Omicron is the most mutated SARS-CoV-2 variant with nearly 50 mutations accumulated in its genome, and is of particular interest and concerns since 26–32 mutations are in the viral spike (S) protein region ( WHO 2021c ), and out of these, 15 are in the receptor-binding domain (RBD) ( ECDC, 2021a ).
WEBDec 23, 2021 · Omicron is a highly divergent variant with a high number of mutations, including 26-32 mutations in the spike protein, some of which may be associated with humoral immune escape potential and higher transmissibility. • As of 22 December 2021, the Omicron variant had been identified in 110 countries across all WHO six
SARS-CoV-2 B.1.1.529 (Omicron) Variant — United States...
WEBDec 16, 2021 · SARS-CoV-2 variant B.1.1.529 (Omicron), first reported to WHO on November 24, 2021, has been designated a variant of concern. Mutations in Omicron might increase transmissibility, confer resistance to therapeutics, or partially escape infection- or vaccine-induced immunity.
SARS-CoV-2 Omicron subvariants evolved to promote further
WEBDec 23, 2022 · We found that MHC-I upregulation was strongly suppressed during SARS-CoV-2 infection in vivo. Notably, the Omicron subvariants showed an enhanced ability to suppress MHC-I compared to the original strain and the earlier SARS-CoV-2 variants of concern (VOCs).
Covid-19 Vaccine Effectiveness against the Omicron (B.1.1.529) …
WEBMar 2, 2022 · In this study, we estimated vaccine effectiveness against symptomatic disease caused by the delta and omicron variants after two doses (primary immunization) of BNT162b2, mRNA-1273, or...
Update on Omicron - World Health Organization (WHO)
WEBOn 26 November 2021, WHO designated the variant B.1.1.529 a variant of concern, named Omicron, on the advice of WHO’s Technical Advisory Group on Virus Evolution (TAG-VE).
Innate immune imprints in SARS-CoV-2 Omicron variant infection ...
WEBNov 16, 2022 · We found that monocyte responses predominated in immune imprints of Omicron convalescents, with IL-1β-associated and interferon (IFN)-responsive signatures with mild and moderate symptoms ...