Antihistamine Types & Side Effects - Cleveland Clinic
WEBJul 26, 2024 · H1 receptor antihistamines. You have H1 receptors throughout your body, including in neurons (brain cells), smooth muscle cells of your airways and blood vessels. Activation of the H1 receptors causes the well-known allergy and anaphylaxis symptoms.
List of Common Antihistamines + Uses & Side Effects - Drugs.com
WEBApr 17, 2023 · Antihistamines block histamine release from histamine-1 receptors and are mostly used to treat allergies or cold and flu symptoms, although some first-generation antihistamines (also called sedating antihistamines) may be used for other conditions, such as nausea or motion sickness.
Antihistamines - StatPearls - NCBI Bookshelf
WEBJul 10, 2023 · Antihistamines are a pharmaceutical class of drugs that act to treat histamine-mediated conditions. There are two main classes of histamine receptors: H-1 receptors and H-2 receptors. Antihistamine drugs that bind to H-1 receptors are generally used to treat allergies and allergic rhinitis.
First-Generation vs. Second-Generation Antihistamines: What’s ... - WebMD
WEBNov 7, 2022 · There are two different types of histamines: H-1 receptor antagonists and H-2 receptor antagonists. Typically, antihistamines that treat H-2 receptor antagonists treat gastrointestinal...
H1 Antihistamines: Current Status and Future Directions
WEBApr 7, 2008 · Efficacy of H 1 antihistamines in allergic diseases. H 1 antihistamines prevent and relieve allergic inflammation and associated symptoms in seasonal/intermittent (perennial/persistent) allergic rhinitis, allergic conjunctivitis, and urticaria (Table 4A).
Evidence-based use of antihistamines for treatment of allergic ...
WEBOct 1, 2023 · Available since the 1940s, H 1 antihistamines are mainstay treatments for allergic conditions such as allergic rhinitis and urticaria. They function as inverse agonists that bind to the H 1 receptor to inhibit histamine-induced inflammation.
H1 antagonist - Wikipedia
WEBantagonist. H1 antagonists, also called H1 blockers, are a class of medications that block the action of histamine at the H 1 receptor, helping to relieve allergic reactions.
Antihistamines and How They're Used - Verywell Health
WEBJun 20, 2023 · Newer oral antihistamines, such as Xyzal (levocetirizine), Zyrtec (cetirizine), Allegra (fexofenadine), and Clarinex (desloratadine), are very effective for the treatment of hay fever. Older antihistamines, like Benadryl (diphenhydramine), chlorpheniramine, and Vistaril (hydroxyzine) work well …
Advances in H1-Antihistamines | New England Journal of Medicine
WEBNov 18, 2004 · Through the H 1 -receptor, histamine has proinflammatory activity and is involved in the development of several aspects of antigen-specific immune response, including the maturation of dendritic...
Histamine and H1-antihistamines: Celebrating a century of …
WEBOct 31, 2011 · We discuss histamine and clinically relevant information about the molecular mechanisms of action of H1-antihistamines as inverse agonists (not antagonists or blockers) with immunoregulatory effects.